The Folger Shakespeare Library in Washington DC has over eighty copies of the so-called First Folio of Shakespeare, more formally titled Mr William Shakespeares Comedies, Histories, & Tragedies, published according to their true original copies. London 1623. A large number of these copies will be circulating on tour soon, in anticipation of the 400th anniversary of Shakespeare's death in 1616. This seems like a good time to ponder the history of this book. How was it assembled after Shakespeare's death by two of his theater colleagues, John Heminges and Henry Condell?